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Ribeiro,M.L.; Santos,A.; Carvalho-Salles,A.B.; Hackel,C.. |
The aim of the present study was to evaluate the distribution of polymorphisms for the androgen receptor (AR) (CAG, StuI, GGN), SRD5A2 (Ala49Thr, Val89Leu) and CYP17 (MspA1) genes that are considered to be relevant for risk of prostate cancer. We studied 200 individuals from two cities in the State of São Paulo, by PCR, PCR-RFLP and ASOH techniques. The allelic frequencies of the autosomal markers and the StuI polymorphism of the AR gene were very similar to those described in most North American and European populations. In relation to the CAG and GGN number of repeats, the study subjects had smaller repeat lengths (mean of 20.65 and 22.38, respectively) than those described in North American, European and Chinese populations. In the present study, 30.5%... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Prostate cancer; Polymorphisms; AR; SRD5A2; CYP17. |
Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000200009 |
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Ribeiro,J. S. Boabaid; Bringel,S. R. B.; Santos,A.. |
Resumo Foram feitas análises de água de quatro igarapés, dos quais dois drenam uma área de campina na Amazônia Central, o terceiro e o quarto drenando "terra firme de floresta", situados ao longo da rodovia BR-174. O estudo foi feito durante um ano ininterrupto, com a finalidade de conhecer o fluxo de saída de nutrientes essenciais do ecossistema da campina em comparação com a floresta de terra firme. Os dados permitem verificar que existe uma curva para cada igarapé, em um ciclo anual, e que apesar das perdas N e P não constituem fatores limitantes para o ecossistema da campina visto que esses elementos são fornecidos pela manta orgânica morta, que é depositada no solo pelos vegetais, e também pela lixiviação de troncos e folhas e ainda pelas chuvas. |
Tipo: Info:eu-repo/semantics/article |
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Ano: 1978 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59671978000300409 |
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Castro,S.M.; Sporleder,H.; Schröeder,R.; Santos,A.; Garcia,V.; Neumann,J.; Costa,S.C.B.. |
We have determined the number of circulating T, B and natural killer cells in renal transplant recipients in order to detect changes during cytomegalovirus (CMV) infections. Serial blood samples were taken from 61 patients on standard triple immunosuppression therapy (cyclosporin A, azathioprine and prednisone). Using two-color flow cytometry analysis, the absolute number of CD3+, CD4+, CD8+, CD19+, CD3+HLA-DR+ and CD16+56+ cells was determined. Forty-eight patients (78.7%) developed active CMV infection, and all of them subsequently recovered. Twenty of the infected patients (32.8%) presented symptoms compatible with CMV disease during the infectious process. The number of lymphocytes and their main subpopulations were normal before the onset of CMV... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Transplantation; Cytomegalovirus; Antigenemia; T lymphocytes. |
Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000600016 |
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